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  • Auswirkungen der physikalischen Therapie mit "Whole Body Vibration" (WBV)
  • Auswirkungen der Behandlung mit passiver Flexion und Extension (PFE) der paralysierten Hinterbeine
  • Auswirkungen der chirurgischen Therapie mit medialer longitudinalen Myelotomie (MLM)
  • Auswirkungen der medikamentösen Therapien mit Riluzol, Erythropoietin und intracellular sigma peptide (ISP) 

angelov.anatomie(at)uni-koeln.de

  • Organogenesis of the intestine
  • Organization of cytoskeletal networks
  • Analysis of succinat dehydrogenase inhibitors

 

olaf.bossinger@uk-koeln.de 

  • Transmissionselektronenmikroskopie in Kooperationsprojekten mit mehreren Kliniken und Instituten
  • Zelluläre Lokalisation und Funktion des Angiotensin II Rezeptors Typ 1
  • Regeneration peripherer Nerven

neiss.anatomie(at)uni-koeln.de

 Molecular control of cell polarity in epithelia and stem cells. We are interested in the molecules that link adherens junctions with the cytoskeleton and are required for the establishment of apical-basal cell polarity. Intriguingly, a subset of these molecules is also involved in the polarization and asymmetric division of stem cells.

 Identification of stemness factors in somatic and germ line stem cells. By a combination of genetics, cell isolation by FACS sorting, next generation RNA sequencing (RNAseq) and functional in vivo assays we aim to identify genes that are required for maintenance of the unique properties of stem cells.

 Functional characterization of Wnt coreceptors in Drosophila. We have generated mutations in the Wnt coreceptors Off-track, Off-track2 and Ror and are currently analyzing their developmental function and the signaling pathways downstream of these receptors.

The model organism of our research is mainly the fruit fly Drosophila, as it is easily accessible to genetic manipulation and is very well suited for cell biological analyses using high-resolution light microscopy.